tecovirimat will increase the stage or effect of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Check for adverse outcomes if coadministered with delicate substrates of those enzymes.

Modafinil appeared to create a focus-related suppression of CYP2C9 exercise, therefore suggesting opportunity for CYP2C9 inhibition; warning if medication which have a slim therapeutic index

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Similarly, it's at this time unknown regardless of whether modafinil can be transmitted to an toddler via breastmilk, and similar cautions use to modafinil use by mothers that are nursing [38].

modafinil will improve the amount or outcome of mavacamten by impacting hepatic enzyme CYP2C19 metabolism. Contraindicated. Strong or reasonable CYP2C19 inhibitors might boost mavacamten systemic exposure, causing coronary heart failure because of systolic dysfunction.

If you think that There's been an overdose, get in touch with your poison Handle center or get healthcare treatment without delay. Be more info wanting to notify or present what was taken, the amount of, and when it happened.

tazemetostat will reduce the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

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This medicine might be used for other uses; check with your health treatment company or pharmacist For those who have thoughts.

rifampin will reduce the extent or effect of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.

If you believe modafinil isn't Operating thoroughly When you have taken it to get a handful of weeks, don't boost the dose. As a substitute, Look at using your doctor.

Modafinil was deemed to the treatment method of ADHD because of its reduce abuse potential than common psychostimulants[23] like methylphenidate and amphetamines.

nevirapine will decrease the extent or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

Nevertheless, not Substantially is at this time regarded concerning the likelihood or opportunity signs of modafinil overdose other than this single case review — so caution is still remarkably recommended when taking this drug, and care should always be taken to take it only as specially directed and instructed by your medical professional.